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Histone Modification Animation PDF Print E-mail
Written by Sebastian Bassi   
Wednesday, 07 October 2009 16:39

Histones are subject to a wide variety of posttranslational modifications including but not limited to, lysine acetylation, lysine and arginine methylation, serine and threonine phosphorylation, and lysine ubiquitination and sumoylation (Vasquero 2003). These modifications occur primarily within the histone amino-terminal tails protruding from the surface of the nucleosome as well as on the globular core region (Cosgrove 2004).

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Pyrosequencing PDF Print E-mail
Written by Administrator   
Friday, 19 June 2009 04:41
Pyrosequencing is a method of DNA sequencing (determining the order of nucleotides in DNA) based on the "sequencing by synthesis" principle, which relies on detection of pyrophosphate release on nucleotide incorporation rather than chain termination with dideoxynucleotides.The technique was developed by Pål Nyrén and his student Mostafa Ronaghi at the Royal Institute of Technology in Stockholm in 1996.
Source: bioisolutions.blogspot.com/2009/05/pyrosequencing.html
Pyrosequencing PDF Print E-mail
Written by Sebastian Bassi   
Saturday, 14 March 2009 21:54

Pyrosequencing™ is sequencing by synthesis, a simple to use technique for accurate and quantitative analysis of DNA sequences.


HIV structure PDF Print E-mail
Written by Administrator   
Saturday, 14 March 2009 20:30

A virus is not a cell, but is made up of genetic instructions contained in a protective shell. A single HIV virus particle is called a virion. It is spherical and one 10,000th of a millimeter in diameter. The protective shell of the virus is known as the viral envelope. It is composed of two layers of fatty molecules. Embedded in the envelope surface is complex HIV protein called the env protein that sticks out of the envelope surface. Env consists of a cap called gp120 and a stem called gp41. The viral core is called the capsid.

Major elements within the viral core are:

Two single strands of HIV RNA. RNA carries genetic instructions that allow the HIV virus to replicate itself.
Three enzymes that are needed for replication of the virus.


Last Updated on Saturday, 14 March 2009 20:49